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BETTING

Cardinals vs. Giants MLB Computer Pick: Frisco Looks to Finish Strong

Tyler Fitzgerald San Francisco Giants Arizona
Tyler Fitzgerald #49 of the San Francisco Giants runs out of the batters box after hitting an RBI double against the Arizona Diamondbacks during the second inning at Chase Field on September 25, 2024 in Phoenix, Arizona. Norm Hall/Getty Images/AFP

We’ve got one more weekend of regular season baseball on the schedule. While there are still a few meaningful games, tread lightly to close the regular season. That said, let’s see what our AI Model wants us to consider at the top-rated sportsbooks.

For more of today’s betting analysis, check out:

MLB Pick


St. Louis Cardinals vs. San Francisco Giants

Friday, September 27, 2024 – 10:15 PM ET at Oracle Park


With no playoff implications, the AI Model thinks the Giants will secure a 4.1-3.7 win at home against the Cardinals. Both teams have hovered around .500 all year, so this prediction is unsurprising.

San Francisco Could Strike Out Less

The San Francisco Giants have struggled with strikeouts throughout the entire season. However, against Miles Mikolas and the Cardinals, those strikeouts could be fewer.

After all, Mikolas has struck out just 16.9% of batters this season and has added only 21.9% of strikeouts through the last 30 days. These are below-average numbers, which is one reason to believe the Giants can put the ball in play and make things happen tonight.

San Francisco still has four batters who have hit a high ISO and wOBA against righties over the last month, including Matt Chapman, who has added a .328 ISO and wOBA of .378.

Landen Roupp’s Good Numbers

The Giants will ride with Landen Roupp. The right-hander also doesn’t earn a high rate of strikeouts. However, he’s held his last 88 opponents to a .038 ISO and wOBA of .213.

He’s been more consistent than Mikolas over the previous 30 days and has an easier lineup to face since the Cardinals have hit just a .140 ISO over the last month against righties.

The Pick

Let’s take the Giants to add the win at -135.

MLB Pick: Giants ML (-135) at Bet365

*The line and/or odds referenced in this article might have changed since the content was published. For the latest information on line movements, visit OddsTrader’s free betting odds tool.

*21+ Seek help with a gambling addiction at 1-800-Gambler

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