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BETTING

MLB Computer Picks for April 5: Cleveland Looks to Tame LA

Brayan Rocchio Cleveland Guardians
Brayan Rocchio #4 of the Cleveland Guardians hits a two-run single against the Los Angeles Angels in the sixth inning at Angel Stadium of Anaheim on April 04, 2025 in Anaheim, California. Ronald Martinez/Getty Images/AFP

All 30 teams are playing an MLB game today! I reviewed all 15 games and asked the AI Model for help finding the best bets. Here’s what you should consider at the top-rated sportsbooks!

Picks Summary

  • Athletics ML (-120)
  • Mariners ML (+110)
  • Guardians ML (-150)

*All odds from Caesars Sportsbook (check our Caesars Sportsbook Review)


Athletics vs. Colorado Rockies

Saturday, April 05, 2025 – 08:10 PM EDT at Coors Field


Our AI Model likes the Athletics to get by the Rockies, 5-4.7 tonight. The Athletics have three wins, while the Rockies have just one. In addition, the Athletics are -120 on the moneyline against the Rockies. There’s value in the Athletics.

Has JP Sears Finally Reached His Potential?

The Athletics are hopeful that JP Sears has finally arrived. The lefty struck out 28% of batters and walked none in his first start.

Tonight, he’ll battle a Rockies lineup that has struck out 30.3% of the time against lefties since last season. Sears is in line for another monster game on the mound.

Will German Marquez Continue To Succeed?

German Marquez will take on Sears in a fun little duel. Marquez was also very good in his season debut, but he’s only thrown in a couple of Major League games in the last couple of seasons due to injury.

He’s not a ground ball pitcher, which doesn’t translate well in Coors Field.

The Pick

Stick with the AI Model and take the Athletics.

MLB Pick: Athletics ML (-120) at Caesars Sportsbook


Seattle Mariners vs. San Francisco Giants

Saturday, April 05, 2025 – 09:05 PM EDT at Oracle Park


The AI Model projects the Mariners will escape with a 4-3.6 win over the Giants. Meanwhile, the Mariners are +110 on the moneyline. There’s clearly some value on Seattle tonight.

Bryce Miller Will Show More Consistency!

The Mariners are looking for more out of Bryce Miller. The righty held 705 batters to a .138 ISO and wOBA of .263 last season. Meanwhile, in his first start this year, Miller only struck out 16.4% of batters and added just 38.9% of ground balls.

He won’t force a high rate of ground balls, but he should be able to earn a high strikeout rate against the Giants. The Giants’ projected lineup has struck out 22.6% of the time against righties and has six batters who have struck out at a high rate against righties since last season.

Miller should have a quality start tonight.

Can We Trust Robbie Ray?

The San Francisco Giants will send out lefty Robbie Ray. He only threw against 129 batters last season but allowed a .198 ISO and wOBA of .319. In his first start this year, Ray gave up a .316 ISO and struck out only 20% of batters. Ray is known for high strikeouts but didn’t get it in his first game.

The Mariners ultimately have much power against lefties in their projected lineup. They’ve hit a .180 ISO as a group since last season.

The Pick

Grab the Mariners at +110.

MLB Pick: Mariners ML (+110) at Caesars Sportsbook


Cleveland Guardians vs. Los Angeles Angels

Saturday, April 05, 2025 – 09:38 PM EDT at Angel Stadium


The AI Model thinks the Guardians will add a 4.6-3.9 win over the Angels on the road. Meanwhile, Cleveland is just -150 on the moneyline. The best play in this game is selecting the Guardians on the moneyline.

Will Tanner Bibee Bounce Back?

Tanner Bibee already started the season with a stomach bug and then pitched four days later and looked average. Bibee struck out only 10% of batters and allowed 37.5% of fly balls with a .167 ISO.

Still, last season, Bibee limited teams to a .309 wOBA and added 26% of strikeouts with 6% of walks. I think he’ll get back on track for this start, be healthy, and be much more prepared for this game.

Meanwhile, he’ll battle the Angels, who have hit just a .323 wOBA against righties since last season. More importantly, the Angels’ projected lineup has struck out more than 24% of the time against righties since last season.

Is Jack Kochanowicz Good?

The Angels will roll with righty starter Jack Kochanowicz. He struck out only 9.4% of batters last season and added just 19% of strikeouts in his first start this season. He’s not going to put away hitters. Meanwhile, he allowed 41.2% of fly balls and only added 29.4% of ground balls in his first start this season.

They’ll have an advantage if the Guardians remain aggressive at the plate and try to attack Kochanowicz early. After all, Jose Ramirez slugged three home runs last night and has the Guardians’ offense moving in the right direction.

The Pick

Take the Guardians at -150.

MLB Pick: Guardians ML (-150) at Caesars Sportsbook

*21+ Seek help with a gambling addiction at 1-800-Gambler

*The line and/or odds referenced in this article might have changed since the content was published. For the latest information on line movements, visit OddsTrader’s free betting odds tool.

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