Week 3 kicks off on September 21 with the New York Giants facing the San Francisco 49ers on the West Coast for a second consecutive game out in the West Coast, just four days after their historic comeback against the Arizona Cardinals, in Week 2.
On Sunday, the Indianapolis Colts visit the Baltimore Ravens, bringing back memories of the Colts’ relocation from Baltimore to Indianapolis. The question is if Anthony Richardson will play after self-reporting concussion symptoms during the win against the Texans, last Sunday. The 1 PM slate also offers an interesting matchup between the Broncos and the Miami Dolphins, with Sean Payton trying to avoid an 0-3 start with the Broncos.
Also, you don’t want to miss out on the action of the divisional showdown between the Patriots and the Jets at MetLife Stadium as Bill Belichick looks to keep preying on Zach Wilson.
Finally, the second Monday Night Football doubleheader of the season features the Eagles against the Buccaneers and the Bengals hosting the Rams.
NFL Week 3 Odds
Below is the complete list of NFL Week 3 odds.Â
| Matchup | Date | Time | Spread | Over/Under |
|---|---|---|---|---|
| Patriots vs. Jets | Thursday, September 19 | 08:15 PM ET | Jets -7 (-120) | 45 |
| Bears vs. Colts | Sunday, September 22 | 01:00 PM ET | Colts -1 (-120) | 46.5 |
| Giants vs. Browns | Sunday, September 22 | 01:00 PM ET | Browns -5.5 (-120) | 43.5 |
| Packers vs. Titans | Sunday, September 22 | 01:00 PM ET | Packers -4 (-120) | 44.5 |
| Eagles vs. Saints | Sunday, September 22 | 01:00 PM ET | Eagles -3 (-120) | 45.5 |
| Chargers vs. Steelers | Sunday, September 22 | 01:00 PM ET | Steelers -1 (-120) | 43.5 |
| Texans vs. Vikings | Sunday, September 22 | 01:00 PM ET | Texans -4 (-120) | 47 |
| Broncos vs. Buccaneers | Sunday, September 22 | 01:00 PM ET | Buccaneers -3 (-120) | 42.5 |
| Panthers vs. Raiders | Sunday, September 22 | 04:05 PM ET | Raiders -4 (-120) | 43.5 |
| Dolphins vs. Seahawks | Sunday, September 22 | 04:05 PM ET | Dolphins -2.5 (-120) | 48.5 |
| Lions vs. Cardinals | Sunday, September 22 | 04:25 PM ET | Lions -3.5 (-120) | 51 |
| 49ers vs. Rams | Sunday, September 22 | 04:25 PM ET | 49ers -4 (-120) | 46.5 |
| Ravens vs. Cowboys | Sunday, September 22 | 04:25 PM ET | Ravens -1 (-120) | 46.5 |
| Chiefs vs. Falcons | Sunday, September 22 | 08:20 PM ET | Chiefs -3.5 (-120) | 50 |
| Jaguars vs. Bills | Monday, September 23 | 07:30 PM ET | Bills -3.5 (-120) | 48.5 |
| Commanders vs. Bengals | Monday, September 23 | 08:15 PM ET | Bengals 6.5Â (-120) | 47.5 |
*Odds via Caesars Sportsbook (check our Caesars Sportsbook Review)
Best NFL Week 3 Spread Available
| Matchup | Current Best Spread Available |
|---|---|
| Patriots vs. Jets | Jets -7 (-120) at Caesars Sportsbook |
| Bears vs. Colts | Colts -1 (-120) at Caesars Sportsbook |
| Giants vs. Browns | Browns -5.5 (-120) at Caesars Sportsbook |
| Packers vs. Titans | Packers -4 (-120) at Caesars Sportsbook |
| Eagles vs. Saints | Eagles -3 (-120) at Caesars Sportsbook |
| Chargers vs. Steelers | Steelers -1 (-120) at Caesars Sportsbook |
| Texans vs. Vikings | Texans -4 (-120) at Caesars Sportsbook |
| Broncos vs. Buccaneers | Buccaneers -3 (-120) at Caesars Sportsbook |
| Panthers vs. Raiders | Raiders -4 (-120) at Caesars Sportsbook |
| Dolphins vs. Seahawks | Dolphins -2.5 (-120) at Caesars Sportsbook |
| Lions vs. Cardinals | Lions -3.5 (-120) at Caesars Sportsbook |
| 49ers vs. Rams | 49ers -4 (-120) at Caesars Sportsbook |
| Ravens vs. Cowboys | Ravens -1 (-120) at Caesars Sportsbook |
| Chiefs vs. Falcons | Chiefs -3.5 (-120) at Caesars Sportsbook |
| Jaguars vs. Bills | Bills -3.5 (-120) at Caesars Sportsbook |
| Commanders vs. Bengals | Bengals 6.5 (-120) at Caesars Sportsbook |
More Weekly NFL Odds Previews
Eager to explore the upcoming NFL schedule for the most recent odds or curious about the odds of a game that has already taken place? Check out our odds preview covering all 18 weeks of the NFL regular season!
